Summary
Occlusion of the circumflex branch of the left coronary artery in rabbits induces a differential response of regional sympathetic activity. The discharges of the splanchnic nerve are increased, and the discharges of a sympathetic nerve twig to the ear are inhibited. This pattern of sympathetic response is accompanied by a fall in arterial blood pressure.
Zusammenfassung
Während Okklusion des R. circumflexus der linken Coronararterie treten beim Kaninchen gegensinnige Änderungen der regionalen Sympathicusaktivität auf: Die Entladungen im N. splanchnicus nehmen zu, die Aktivität in einem Sympathicusast zum Ohr nimmt ab. Der arterielle Blutdruck fällt ebenfalls ab.
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Delius, W., Hagbarth, K.-E., Hongell, A., Wallin, B. G.: Manoeuvres affecting sympathetic outflow in human skin nerves. Acta physiol. scand.84, 177–186 (1972).
Hanley, H. G., Costin, J. C., Skinner, N. S., Jr.: Differential reflex adjustments in cutaneous and muscle vascular beds during experimental coronary artery occlusion. Amer. J. Cardiol.27, 513–521 (1971).
Iriki, M., Walther, O.-E., Pleschka, K., Simon, E.: Regional cutaneous and visceral sympathetic activity during asphyxia in the anesthetized rabbit. Pflügers Arch.322, 167–182 (1971).
Karim, F., Kidd, C., Malpus, C. M., Penna, P. E.: The effects of stimulation of the left atrial receptors on sympathetic efferent nerve activity. J. Physiol. (Lond.)227, 243–260 (1972).
Riedel, W., Iriki, M., Simon, E.: Regional differentiation of sympathetic activity during peripheral heating and cooling in anesthetized rabbits. Pflügers Arch.332, 239–247 (1972).
Skinner, N. S., Jr., Hanley, H. G., Inglesby, T. V., Costin, J. C., Sachs, R. G., Silverstein, H. R., Raizner, A.: Differential reflex vascular responses in specific tissues with stimulation of reflexogenic areas. Fed. Proc.30, Abstr. 397 (1971).
Walther, O.-E., Iriki, M., Simon, E.: Antagonistic changes of blood flow and sympathetic activity in different vascular beds following central thermal stimulation. II. Cutaneous and visceral sympathetic activity during spinal cord heating and cooling in anesthetized rabbits and cats. Pflügers Arch.319, 162–184 (1970).
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This work was supported by the Deutsche Forschungsgemeinschaft.
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Kullmann, R., Junk, H.G. Differential sympathetic response during coronary occlusion. Res. Exp. Med. 160, 317–320 (1973). https://doi.org/10.1007/BF01851471
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DOI: https://doi.org/10.1007/BF01851471