Skip to main content
Log in

Cytological effects of two contraceptives

  • Published:
Genetica Aims and scope Submit manuscript

Abstract

The cytological effects of the contraceptives Conovid E and Lyndiol were studied onAllium root tips. In the stronger concentrations Conovid E has a pronounced stathmokinetic effect, producing polyploidy, possibly aneuploidy, star metaphases, anaphase bridges. Lyndiol did not have any effect on metaphase, although anaphase irregularities were observed. The difference between the two substances is explained at least in part by the presence of an O=atom in the progesteron component of Conovid, which is not present in the progesteron component of Lyndiol.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Barber, H. &H. Callan (1943). The effects of cold and colchicine on mitosis in the newt.Proc. Roy. Soc. London, B131: 258–271.

    Google Scholar 

  • Barthelmess A. &A. El Kabarity (1962). Chemisch induzierte multipolare Mitosen III,Protoplasma 54: 455–475.

    Google Scholar 

  • Berger, A. (1950). Colchicine Derivatives III. Effect of mitotic activity of mouse spermatogonia.Cancer 3: 134–141.

    PubMed  Google Scholar 

  • Eigsti, C. F. &P. Dustin (1955). Colchicine in agriculture, medicine, biology & chemistry. Iowa State College Press, Ames, U.S.A.

    Google Scholar 

  • Hakeem, H. &S. Amer (1966). Meiotic effects of water extracts of some contraceptive tablets.Naturwissenschaften 53: 184.

    Google Scholar 

  • Kabarity, A. (1966). Cardiazol, a new stathmokinetic chemical.Arzneimittel Forschung. In press.

  • Kabarity, A. &S. Khodary (1967). Merokinetic effect of Anovlar.The Lancet 1: 853.

    Google Scholar 

  • Lipschutz, A., R. Iglesias, S. Salinas & VeraI. Panasevich (1966). Experimental conditions under which contraceptive steroids may become toxic.Nature 212: 686–688.

    Google Scholar 

  • Ludford, R. J. (1936). The action of toxic substances upon the division of normal and malignant cells in vitro and in vivo.Arch. Exp. Zell Forsch. und Mikr. Anat. 18: 411–441.

    Google Scholar 

  • Pernice, B. (1889). Sulla carionesi delle cellule epiteliali e dell endotelio dei vasi della mucosa dello stomaco e dell intestino, nello studio della gastroenterite sperimentale.Sicilia Med. 1: 265–279.

    Google Scholar 

  • Peters, J. (1946). A cytological study of mitosis in the cornea ofTriturus viridescens during recovery after colchicine treatment.J. Exp. Zool. 103: 33–56.

    Google Scholar 

  • Östergren, G. (1943). Elastic chromosome repulsions.Hereditas 29: 444–450.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kabarity, A., Khodari, S. Cytological effects of two contraceptives. Genetica 38, 184–190 (1967). https://doi.org/10.1007/BF01507457

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01507457

Keywords

Navigation