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Indolopyridines with a hetero atom at a position of fusion 8. Reductive C-alkylation of indolo[2,1-a]isoquinolone

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Indolo(2,1-a]isoquinoline was alkylated at C(11) under catalytic hydrogenation conditions over rhenium heptasulfide in a medium of various alcohols. It was shown that the alkylation occurs by an electrophilic substitution mechanism and the yield of the products increases with decreasing acidity of the alcohols.

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References

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Communication 7, see [1]

Translated from Khimiya Geterotsikiicheskikh Soedinenii, No. 3, pp. 377–380, March, 1994.

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Soldatova, S.A., Alarkon, J.A., Mamyrbekova, Z.A. et al. Indolopyridines with a hetero atom at a position of fusion 8. Reductive C-alkylation of indolo[2,1-a]isoquinolone. Chem Heterocycl Compd 30, 331–334 (1994). https://doi.org/10.1007/BF01165700

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  • DOI: https://doi.org/10.1007/BF01165700

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