Abstract
The effects of applying electromicrostimulation to areas of the caudate nucleus with different neuronal activity patterns were investigated during chronic experiments on four cats. Caudate sites containing neurons responding to presentation of various sensory stimuli were selected for the first set of experiments and those where no neuronal activity manifested in the second series. Histological verification of electrolytic marker sites produced by electrical stimulation took place at the end of each experimental sequence and the cell types surrounding these lesions were examined. Microelectrostimulation consistently produced movement in the animal in the first set of experiments; markers were located along the surface of striosomes among large-sized cells, bundles of fibers, and blood vessels. In the second, electrical stimulation produced no alteration in naturally occurring animal behavior; markers were located within striosomes in accumulations of small- and medium-sized cells. A survey of the findings obtained would confirm our hypothesis that the neurons from which activity had been recorded by extracellular techniques in the caudate nucleus are large-sized cells with long axons.
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Institute for Research into Information Transmission, Academy of Sciences of the USSR, Moscow. Translated from Neirofiziologiya, Vol. 22, No. 2, pp. 162–171, March–April, 1990.
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Rodionova, E.I., Pigarev, I.N. & Leontovich, T.A. Effects of applying microelectrostimulation to different cell type zones in the caudate nucleus. Neurophysiology 22, 123–130 (1990). https://doi.org/10.1007/BF01052159
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DOI: https://doi.org/10.1007/BF01052159