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Production of 4-decanolide by semicontinuous fermentation of Tyromyces sambuceus

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Summary

Tyromyces sambuceus was cultivated in a stirred tank reactor under semicontinuous conditions for 70 days. Over longer periods of time in submersion, values of 220 and 330 mg·L−1 of 4-decanolide could be maintained; after dispersion of the headspace mycelia, a single peak product concentration of 880 mg·L−1 was attained. The productivity was subject to large variations, peak values were 18 and 11 mg·L−1·h−1. Depending on the culture conditions, specific growth rates of up to 0.05 h−1 were reached.

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Authors and Affiliations

  1. Institute of Food Technology and Analytical Chemistry, Technical University of Munich, D-8050, Freising-Weihenstephan, FRG

    G. -F. Kapfer, R. G. Berger & F. Drawert

Authors
  1. G. -F. Kapfer
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  2. R. G. Berger
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  3. F. Drawert
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Kapfer, G.F., Berger, R.G. & Drawert, F. Production of 4-decanolide by semicontinuous fermentation of Tyromyces sambuceus. Biotechnol Lett 11, 561–566 (1989). https://doi.org/10.1007/BF01040036

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  • DOI: https://doi.org/10.1007/BF01040036

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