Conclusions
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1.
4-Aminopyrimidines react with hexafluoroacetone to give pyrimidooxazines and pyrimidooxadiazines.
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2.
An account is given of the C5 aminoalkylation of 1,3-dimethyluracil by the trifluoroacetylimines of hexafluoroacetone and of the methyl ester of trifluoropyruvic acid.
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V. D. Sviridov, N. D. Chkanikov, M. V. Galakhov, et al., Izv. Akad. Nauk SSSR, Ser. Khim., No. 6, 1433 (1987).
S. Ya. Mel'nik, A. A. Bakhmedova, T. P. Nedorezova, et al., Bioorg. Khim.,7, No. 7, 1047 (1981).
S. Ya. Mel'nik, N. A. Bakhmedova, I. V. Yartseva, et al., Bioorg. Khim.,13, No. 7, 934 (1987).
V. D. Sviridov, N. D. Chkanikov, A. F. Kolomiets, and A. V. Fokin, Izv. Akad. Nauk SSSR, Ser. Khim., No. 11, 2554 (1985).
A. V. Fokin, N. D. Chkanikov, V. L. Vershinin, and A. F. Kolomiets, Izv. Akad. Nauk SSSR, Ser. Khim., No. 4, 949 (1985).
B. I. Ionin, V. A. Ershov, and A. I. Kol'tsov, NMR Spectroscopy in Organic Chemistry [in Russian], Khimiya, Leningrad (1983).
G. C. Levy and G. L. Nelson, Carbon-13 Nuclear Magnetic Resonance for Organic Chemists, Wiley-Interscience, New York (1972).
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For previous communication, see [1].
Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 7, pp. 1656–1659, July, 1989.
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Sviridov, V.D., Chkanikov, N.D., Korbukh, I.A. et al. Reaction of hexafluoroacetone and trifluoroacetylimines of polyfluorocarbonyl compounds with derivatives of pyrimidine. Russ Chem Bull 38, 1519–1522 (1989). https://doi.org/10.1007/BF00978450
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DOI: https://doi.org/10.1007/BF00978450