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Synthesis of methoprene via electroreduction of the thiophene ring

  • Organic Chemistry
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Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

The synthesis of the juvenoid methoprene and its 2Z,4E isomer (as a ∼1∶1 mixture) has been accomplished, one of the steps being the electrochemical reduction of a 3,5-dialkylthiophene-2-carboxylic acid.

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Authors and Affiliations

  1. N. D. Zelinskii Institute of Organic Chemistry, Academy of Sciences of the USSR, Moscow

    A. V. Lozanova, V. P. Gul'tyai, A. N. Karaseva & A. M. Moiseenkov

Authors
  1. A. V. Lozanova
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  2. V. P. Gul'tyai
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  3. A. N. Karaseva
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  4. A. M. Moiseenkov
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Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 6, pp. 1370–1373, June, 1983.

The authors thank E. A. Pridantseva for the gift of a sample of methoprene, and Z. G. Isaeva for valuable discussions of the results.

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Lozanova, A.V., Gul'tyai, V.P., Karaseva, A.N. et al. Synthesis of methoprene via electroreduction of the thiophene ring. Russ Chem Bull 32, 1241–1245 (1983). https://doi.org/10.1007/BF00953165

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  • DOI: https://doi.org/10.1007/BF00953165

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