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Syntheses in the quinoline series

III. 2-Formyl-8-hydroxyquinoline derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

2-Formyl-8-hydroxyquinoline and 5,7-dimethyl-2-formyl-8-hydroxyquinoline derivatives were synthesized. The use of nitrophenols as the oxidizing agents in the reaction of the appropriate aminophenols with crotonaldehyde leads to a substantial increase in the yields of quinaldines. According to the IR spectroscopic data, the oximes of the formylhydroxyquinolines have a syn configuration.

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Authors and Affiliations

  1. All-Union Scientific-Research Institute of Chemical Reagents and Ultrapure Chemical Substances, 107258, Moscow

    I. A. Krasavin, Yu. P. Radin, Yu. S. Ryabokobylko, B. V. Parusnikov & V. M. Dziomko

Authors
  1. I. A. Krasavin
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  2. Yu. P. Radin
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  3. Yu. S. Ryabokobylko
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  4. B. V. Parusnikov
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  5. V. M. Dziomko
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Additional information

See [1] for communication II.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 235–239, February, 1978.

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Krasavin, I.A., Radin, Y.P., Ryabokobylko, Y.S. et al. Syntheses in the quinoline series. Chem Heterocycl Compd 14, 190–194 (1978). https://doi.org/10.1007/BF00945333

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  • DOI: https://doi.org/10.1007/BF00945333

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