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Eine einfache Dreikomponentensynthese von Pyrido [1,2-a] pyrimidinen

Syntheses with nitriles, XLIV: A simple synthesis for pyrido-[1,2-a] pyrimidines

Synthesen mit Nitrilen, 44 Mitt.

  • Organische Chemie und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Abstract

N-(2-Pyridyl)-aminomethylene-malononitriles3 are obtained in good yields by heating 2-aminopyridines with malononitrile in the presence of orthoformiates. Acid hydrolysis of3 leads to pyrido [1,2-a]pyrimidines (5,6, and7).

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Authors and Affiliations

  1. Institut für Organische Chemie, Abteilung für Organische Chemie I, Universität Graz, Heinrichstra\e 28, A-8010, Graz, Österreich

    Hans Werner Schmidt &  Hans Junek

Authors
  1. Hans Werner Schmidt
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  2. Hans Junek
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Schmidt, H.W., Junek, H. Eine einfache Dreikomponentensynthese von Pyrido [1,2-a] pyrimidinen. Monatshefte für Chemie 108, 517–524 (1977). https://doi.org/10.1007/BF00912794

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  • DOI: https://doi.org/10.1007/BF00912794

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