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Analogs of carbohydrate-exchange coenzymes

Communication 1. Synthesis of 3-methyluridine 5'-pyrophosphate glucosyl ester

  • Organic and Biological Chemistry
  • Published:
Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Summary

  1. 1.

    3-Methyluridine 5'-pyrophosphate glucosyl ester was synthesized.

  2. 2.

    Taking the case of the preparation of 3-methyluridine 5'-phosphate as example, we developed a new method for the synthesis of pyrimidine nucleotides: Phosphorylation with dimorpholinophosphinic chloride.

  3. 3

    A description was given of the application of thin-layer chromatography on alumina for the separation of protected nucleosides.

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Authors and Affiliations

  1. Institute for the Chemistry of Natural Compounds, Academy of Sciences, USSR

    N. K. Kochetkov, É. I. Budovskii & V. N. Shibaev

Authors
  1. N. K. Kochetkov
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  2. É. I. Budovskii
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  3. V. N. Shibaev
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Additional information

The authors acknowledge their great indebtedness to N. D. Gabridlyan, M. A. Crachev, and G. I. Eliseeva for the help that they have given in this work.

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Kochetkov, N.K., Budovskii, É.I. & Shibaev, V.N. Analogs of carbohydrate-exchange coenzymes. Russ Chem Bull 11, 971–976 (1962). https://doi.org/10.1007/BF00905216

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  • DOI: https://doi.org/10.1007/BF00905216

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