Abstract
Investigations of the thymus-dependent and thymus-independent lymphocyte populations in patients with chronic renal failure showed that mainly the system of T-lymphocytes is depressed in these patients. Both populations of lymphocytes participate in the rejection reaction, but to different extents. In inflammatory conditions, suppurative liquefaction of the tissues, furunculosis, hematoma, and so on, the T-lymphocytes are activated only slightly but the B-lymphocytes considerably in response to stable doses of immunodepressants. The proof of the participation of both lymphocyte populations in the rejection reaction provides fresh approaches to the diagnosis of various pathological states in the recipients.
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Dzerzhinskaya, I.I. T- and B-lymphocytes in patients with chronic renal failure and recipients of an allografted cadaveric kidney in the period immediately after transplantation. Bull Exp Biol Med 87, 158–160 (1979). https://doi.org/10.1007/BF00833977
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DOI: https://doi.org/10.1007/BF00833977