Abstract
The course of pressor and depressor responses was studied during normal activity of the animal and after partial resection of the body and tail of the pancreas in experiments on 39 sexually mature mongrel dogs. The principal indices characterizing changes in the pressor response to noradrenalin and the depressor response to bradykinin and kallikrein were determined before and 10–12 days after resection of the pancreas. Removal of the body and tail of the pancreas was shown to potentiate pressor responses to noradrenalin and depressor responses to bradykinin and kallikrein; the initial negative chronotropic effect of catecholamines on the heart was strenghtened; the positive chronotropic effects of noradrenalin, bradykinin, and kallikrein on the heart also were strengthened.
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Laboratory of Pathophysiology of Hemostasis and the Peripheral Circulation, Research Institute of Clinical and Experimental Medicine, Ministry of Health of the Azerbaijan SSR Baku. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 87, No. 2, pp. 103–106, February, 1979.
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Rzaev, N.M., Abaskulieva, L.I. & Khanumova, T.A. Changes in pressor and depressor responses after partial pancreatectomy. Bull Exp Biol Med 87, 76–78 (1979). https://doi.org/10.1007/BF00833951
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DOI: https://doi.org/10.1007/BF00833951