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Chinazolincarbonsäuren, 5. Mitt.: Synthese von 1,4-Dihydro-chinazolin-4-on-1-yl-essigsäuren und Estern

Quinazoline carboxylic acids, V: 1,4-Dihydro-quinazoline-4-on-1-yl-acetic acids and esters

  • Organische Chemie Und Biochemie
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Abstract

1,4-Dihydro-quinazoline-4-on-1-yl-acetic acids5 were prepared by reaction of 3,1-benzoxazine-2,4-diones1 with ammonia to2. Cyclisation of2 gave4 and their hydrolysis lead to5. 2-Substituted quinazolinones9 could be obtained by reaction of2 with acid chlorides or by reaction of1 with amidines. Quinazolinone8 was synthesized in a similar way. The substituted 2-aminobenzamide10 showed a reaction behaviour different from that of2.

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Authors and Affiliations

  1. Institut für Biochemie der Pflanzen, Akademie der Wissenschaften der DDR, DDR-4020, Halle, Deutsche Demokratische Republik

    Manfred Süsse & Siegfried Johne

Authors
  1. Manfred Süsse
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  2. Siegfried Johne
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Dem Andenken von Dr.Wolfgang Truppe († 24. 11. 1984) gewidmet.

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Süsse, M., Johne, S. Chinazolincarbonsäuren, 5. Mitt.: Synthese von 1,4-Dihydro-chinazolin-4-on-1-yl-essigsäuren und Estern. Monatsh Chem 117, 499–509 (1986). https://doi.org/10.1007/BF00810899

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  • DOI: https://doi.org/10.1007/BF00810899

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