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Role of thymus-dependent cells in splenic colony formation

  • Microbiology and Immunology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Treatment of bone marrow with serum reacting with theta-antigen, irrespective of the presence of complement, sharply reduces the ability of its cells to form splenic colonies. Injection of thymus cells into the recipient together with bone marrow cells considerably reduces the effect of this serum and substantially increases splenic colony formation. It is suggested that the antiserum inactivates a cell population in the bone marrow that is essential for colony formation in the spleen, but which differs from the pluripotent stem cells-probably the T cell population

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Poverennyi, A.M., Semina, O.V., Semenets, T.N. et al. Role of thymus-dependent cells in splenic colony formation. Bull Exp Biol Med 85, 774–775 (1978). https://doi.org/10.1007/BF00806162

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  • DOI: https://doi.org/10.1007/BF00806162

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