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Changes in electrogenic properties of striated muscle fibers in experimental botulism

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Changes in the electrical parameters of fibers of fast and slow muscles were studied during the development of local botulism in rats. In the early stage of poisoning the membrane potential (MP) of fibers of both fast and slow muscles fell. In the late stage of poisoning, marked depolarization of the membrane was accompanied by a change in the input resistance and time constant (RC) of the membrane, rheobase currents, and amplitude of the action potentials evoked by direct intracellular stimulation. Changes in the electrical parameters were more marked in fast muscle fibers.

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Authors
  1. V. V. Morrison
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Morrison, V.V. Changes in electrogenic properties of striated muscle fibers in experimental botulism. Bull Exp Biol Med 84, 1226–1229 (1977). https://doi.org/10.1007/BF00805867

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  • DOI: https://doi.org/10.1007/BF00805867

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