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Investigation of the ultrastructure of neuromuscular synapses in the Lambert-Eaton myasthenic syndrome

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The ultrastructure of neuromuscular synapses of patients with the Lambert—Eaton myasthenic syndrome was investigated. An increased content of synaptic vesicles in the axon terminals and an increase in the number and depth of anastomosing synaptic folds were found in most synapses. Local destructive changes were detected in the terminals of some synapses. The observations confirm the view that this syndrome is based on a disturbance of the liberation of mediator from the presynaptic structures.

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Authors
  1. L. L. Babakova
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  2. E. A. Kolomenskaya
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  3. N. V. Ostrovskaya
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  4. O. M. Pozdnyakov
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Babakova, L.L., Kolomenskaya, E.A., Ostrovskaya, N.V. et al. Investigation of the ultrastructure of neuromuscular synapses in the Lambert-Eaton myasthenic syndrome. Bull Exp Biol Med 81, 98–100 (1976). https://doi.org/10.1007/BF00800181

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  • DOI: https://doi.org/10.1007/BF00800181

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