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Activity of serum lysosomal enzymes in rats with experimental lead poisoning

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of experimental lead poisoning on the permeability of the lysosomal membrane was investigated in albino rats. Activation of two lysosomal enzymes, α-mannosidase and β-acetylglucosaminidase, was found in the blood serum as early as on the third day of daily administration of lead acetate (20 mg/kg) to the rats. Innury to the lysosomal membrane evidently plays an important role in the pathogenesis of lead poisoning.

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Authors
  1. I. Apostolov
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  2. Z. Zapryanov
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  3. V. Gylybova
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Apostolov, I., Zapryanov, Z. & Gylybova, V. Activity of serum lysosomal enzymes in rats with experimental lead poisoning. Bull Exp Biol Med 82, 1337–1339 (1976). https://doi.org/10.1007/BF00799468

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  • DOI: https://doi.org/10.1007/BF00799468

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