Abstract
In acute experiments on unanesthetized, curarized rats in which cortical unit activity was recorded the threshold doses of diazepam influencing spontaneous and evoked unit activity of sensomotor and visual cortical neurons were determined. Diazepam was shown to inhibit spontaneous and evoked activity of sensomotor cortical neurons in much smaller doses than it inhibited visual cortical unit activity. It is postulated that the neurons of the anterior zones of the cortex are more sensitive to diazepam than neurons of the limbic structures and reticular formation.
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Bulaev, V.M., Ostrovskaya, R.U. Effect of diazepam on unit activity of the rat sensomotor and visual cortex. Bull Exp Biol Med 83, 188–190 (1977). https://doi.org/10.1007/BF00799418
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DOI: https://doi.org/10.1007/BF00799418