Changes in the cardiac output and general peripheral resistance after obstruction of a coronary artery

Summary

The left subclavicular, both carotid and femoral arteries were shunted; then the brachiocephalic artery and aorta were obstructed, distal to the origin of the left subclavicular artery. The output of the left ventricle, excluding that portion of it which flows into the coronary arteries, entered the rotameter through theleft subclavicular artery and flowed into the distal sections of carotid arteries and the proximal sections of the femoral artery. The average blood pressure in the system was measured by an electric manometer. From these data, general peripheral resistance could be estimated according to the data obtained. An average blood pressure of 80–100 mm Hg is the best at which to study the changes of hemodynamic indices occurring after obstruction of the coronary artery.