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Antibodies to single-helical DNA in the sera of healthy persons and laboratory animals

  • Microbiology and Immunology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Serologic reactions using formalinized erythrocytes sensitized with DNA were used to establish the presence of antibodies to monospiral DNA in the sera of healthy persons and various species of test animals. It was shown on the example of the guinea pig sera that the titer of antibodies increased with the age of animals. The above-mentioned antibodies were neutralized by formaldehyde concentrations of 0.2% and higher.

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Literature Cited

  1. G. P. Georgiev, Tsitologiya, No. 2 (1960), p. 186.

    Google Scholar 

  2. M. I. Levi et al., Zh. Mikrobiol., No. 10 (1962), p. 40.

    Google Scholar 

  3. A. M. Poverennyi, Biokhimiya, No. 5 (1959), p. 777.

    Google Scholar 

  4. A. M. Poverennyi and M. I. Levi, Biokhimiya, No. 1 (1964), p. 80.

    Google Scholar 

  5. O. P. Chepinoga, Ukr. Biokhim. Zh., No. 4 (1959), p. 603.

    Google Scholar 

  6. J. Dubert et al., Ann. Inst. Pasteur, Vol. 84 (1953), p. 370.

    Google Scholar 

  7. L. Grossman, D. Stollar, and K. Herrigton, J. Chim. Phys., Vol. 58 (1961), p. 1078.

    Google Scholar 

  8. D. Stollar and L. Levine, J. Immunol., Vol. 87 (1961), p. 477.

    Google Scholar 

  9. D. Stollar, L. Levine, and J. Marmur, Biochim. Biophys. Acta, Vol. 61 (1962), p. 7.

    Google Scholar 

  10. D. Stollar and L. Levine, Arch. Biochem., Vol. 101 (1963), p. 417.

    Google Scholar 

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Levi, M.I., Poverennyi, A.M. & Buravchenko, B.M. Antibodies to single-helical DNA in the sera of healthy persons and laboratory animals. Bull Exp Biol Med 62, 1143–1145 (1966). https://doi.org/10.1007/BF00795461

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  • DOI: https://doi.org/10.1007/BF00795461

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