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Spontaneous chromosomal aberrations in oogenesis of laboratory rats

  • Experimental Genetics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Of 861 oocytes with chromosomes suitable for karyotyping and accurate counting, 797 (92.7%) had the normal number of chromosomes, 64 (7.5%) had aneuploidy, four (0.4%) hyperploidy, and in the remaining 60 there was a deficiency of chromosomes (hypoploidy). Hypoploidy was often caused by artefacts. The percentage of spontaneous aneuploidy in rat oogenesis is evidently about 0.8, much lower than the percentage of spontaneous aneuploidy in mouse oogenesis.

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Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 80, No. 8, pp. 103–106, August, 1975.

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Dyban, A.P., Chebotar', N.A. Spontaneous chromosomal aberrations in oogenesis of laboratory rats. Bull Exp Biol Med 80, 971–974 (1975). https://doi.org/10.1007/BF00789285

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  • DOI: https://doi.org/10.1007/BF00789285

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