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The effect of pentaphene and strychnine on the polysynaptic reflexes of different sections of the spinal cord

  • Biochemistry and Biophysics
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Summary

The effect of Pentaphene and strychnine on the polysynaptic reflexes of the cervical and lumbar sections of the spinal cord was studied on spinal cats by electrophysiological methods. The material was statistically analyzed. It was established that Pentaphene preponderantly depresses, and that strychnine enhances the reflex activity of the lumbar spinal cord segments.

It is known that it is toward the cranium that the changes of the spinal cord functions develop in many pathologic processes attended by affection of the motor apparatus. This suggests that the data obtained regarding pentaphene and strychnine are a particular case of a more general rule governing the reflex action change occurring in the spinal cord in pathologic conditions.

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Il'inskii, O.B. The effect of pentaphene and strychnine on the polysynaptic reflexes of different sections of the spinal cord. Bull Exp Biol Med 49, 589–592 (1960). https://doi.org/10.1007/BF00782112

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