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Investigations of benzimida zole derivatives

XXIII. Reaction of 2-aminomethylbenzimidazole and its 1-methyl derivative with nitrous acid

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 2-aminomethyl- and 2-aminomethyl-1-methylbenzimidazoles with nitrous acid was investigated. The reaction proceeds with nitrogen evolution with excess hydrochloric or hydrobromic acids to form 2-chloro- and 2-bromomethylbenzimidazoles, while 2-benzimidazolylmethylnitrolic acids and other products are obtained with excess nitrous acid.

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Author information

Authors and Affiliations

  1. Rostov-on-Don State University, USSR

    N. K. Chub, E. B. Tsupak & A. M. Simonov

Authors
  1. N. K. Chub
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  2. E. B. Tsupak
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  3. A. M. Simonov
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Additional information

For Communication XXII, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1393–1396, October, 1970.

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Chub, N.K., Tsupak, E.B. & Simonov, A.M. Investigations of benzimida zole derivatives. Chem Heterocycl Compd 6, 1300–1303 (1970). https://doi.org/10.1007/BF00755082

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  • DOI: https://doi.org/10.1007/BF00755082

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