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Circadian effects of hydrocortisone on the blood of the newt,Notophthalmus viridescens

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Summary

Differential counts of the leucocytes of newts,Notophthalmus viridescens, were made at four times of day (2∶00, 9∶00, 14∶00 and 21∶00), 72 hours after the injection of hydrocortisone acetate (experimentais) or distilled water (controls). At all times, increases in neutrophils and decreases in lymphocytes were observed in experimentais as compared to the controls (Table 1). The increases in neutrophils in the experimental newts were most pronounced at 14∶00, and the decreases in the lymphocytes were greatest at 21∶00. The least degrees of neutrophilia and lymphopenia occurred at 9∶00. Consequently, circadian variations in response to the hydrocortisone are indicated. The possible mechanism of mediation of the variations is discussed.

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References

  • Bennett, M. F., Alspaugh, J. K.: Some changes in the blood of frogs following administration of hydrocortisone. Va. J. Sci.15, 76–79 (1964)

    Google Scholar 

  • Bennett, M. F., Gaudio, C. A., Johnson, A. O., Spisso, J. H.: Changes in the blood of newts,Notophthalmus viridescens, following the administration of hydrocortisone. J. comp. Physiol.80, 233–237 (1972)

    Article  CAS  Google Scholar 

  • Bennett, M. F., Harbottle, J. A.: The effects of hydrocortisone on the blood of tadpoles and frogs,Rana catesbeiana. Biol. Bull.135, 92–95 (1968)

    Article  CAS  PubMed  Google Scholar 

  • Bennett, M. F., Johnson, A. O.: Osmotic stress, ACTH and the white blood cell picture in newts,Notophthalmus viridescens. J. comp. Physiol.82, 333–338 (1973)

    Article  Google Scholar 

  • Bennett, M. F., Staley, J.: Cycles of motor activity in the newt,Triturus viridescens. Anat. Rec.137, 339 (1960)

    Google Scholar 

  • Dalton, A. J., Selye, H.: The blood picture and the blood sugar changes during the alarm reaction. Anat. Rec.72 (Suppl.), 48–49 (1938)

    Google Scholar 

  • Himstedt, W.: Die Tagesperiodik von Salamandriden. Oecologia (Berl.)8, 194–208 (1971)

    Article  Google Scholar 

  • Reifenstein, G. H. Ferguson, J. H., Weiskotten, H. G.: Studies on leukocytosis. I. Hourly leukocyte variations of normal rabbits. Amer. J. Path.17, 219–231 (1941)

    CAS  PubMed  PubMed Central  Google Scholar 

  • Sharp, G. W. G.: Reversal of diurnal leucocyte variations in man. J. Endocr.21, 107–114 (1960a)

    Article  Google Scholar 

  • Sharp, G. W. G.: The effect of light on diurnal leucocyte variations. J. Endocr.21, 213–218 (1960b)

    Article  Google Scholar 

  • Selye, H.: In: The physiology and pathology of exposure to stress, p. 1–792. Montreal: Acta, Inc. 1950

    Google Scholar 

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Authors and Affiliations

  1. Department of Biology, Sweet Briar College, Sweet Briar, Virginia, USA

    Charlene Reed &  Miriam F. Bennett

  2. Department of Biology, Colby College, 04901, Waterville, Maine, USA

    Miriam F. Bennett

  3. Department of Biological Sciences, The Florida State University, 32306, Tallahassee, Florida, USA

    Charlene Reed

Authors
  1. Charlene Reed
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  2. Miriam F. Bennett
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Supported in part by National Science Foundation grant, GY-7661, to Sweet Briar College.

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Reed, C., Bennett, M.F. Circadian effects of hydrocortisone on the blood of the newt,Notophthalmus viridescens . J. Comp. Physiol. 86, 59–63 (1973). https://doi.org/10.1007/BF00694478

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  • DOI: https://doi.org/10.1007/BF00694478

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