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The influence of flow rates and flow distributions on diffusion controlled transport across the isolated guinea pig placenta

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Summary

The influence of flow rates and flow distributions on diffusion controlled transport across the isolated guinea pig placenta was investigated.

It was shown that the transport of antipyrine and tritiated water could be explained by simple diffusion and concluded that the maternal and fetal circulations are directed countercurrently. Antipyrine and tritiated water were also used to calculate which part of the maternal and fetal circulations were directed away from the exchange area. One of the models developed by Meschia (1) was changed to account for existing shunts in the maternal and fetal circulations.

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Authors and Affiliations

  1. Department of Chemical Pathology, Faculty of Medicine, Earasmus University Rotterdam, Rotterdam, The Netherlands

    B. K. van Kreel & J. P. van Dijk

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  1. B. K. van Kreel
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  2. J. P. van Dijk
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van Kreel, B.K., van Dijk, J.P. The influence of flow rates and flow distributions on diffusion controlled transport across the isolated guinea pig placenta. J Comp Physiol B 115, 255–264 (1977). https://doi.org/10.1007/BF00692535

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  • DOI: https://doi.org/10.1007/BF00692535

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