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A new case of Pick's disease

Anatomical and ultrastructural studies

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Summary

The fine structure of a cortical frontal biopsy of Pick's disease is described. Pick bodies appear made of unbranched 120 Å neurofilaments, sometimes clustered in geometrical pattern. Post-mortem examination, performed 8 years later, reveals typical lesions. The characteristics of Pick bodies are discussed.

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This work was supported by INSERM, grant no. 76.5-206-6

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Mikol, J., Brion, S., Guicharnaud, L. et al. A new case of Pick's disease. Acta Neuropathol 49, 57–61 (1980). https://doi.org/10.1007/BF00692220

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  • DOI: https://doi.org/10.1007/BF00692220

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