Summary
Rats given nerve in saline intraperitoneally failed to develop allergic neuritis when challenged with nerve in adjuvant 2 weeks later. The serum of protected rats prevented sensitized lymph node cells, from rats immunized only with nerve in adjuvant, from demyelinating rat peripheral nerve cultures.
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This work was supported in part by Special Fellowship NB 01787 from the National Institute of Neurological Diseases and Stroke (Dr. Lehrich), and by USPHS Grant NDS 06021 and Grant 428 from the National Multiple Sclerosis Society.
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Lehrich, J.R., Arnason, B.G. Suppression of experimental allergic neuritis in rats by prior immunization with nerve in saline. Acta Neuropathol 18, 144–149 (1971). https://doi.org/10.1007/BF00687602
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DOI: https://doi.org/10.1007/BF00687602