Acta Neuropathologica

, Volume 18, Issue 2, pp 144–149 | Cite as

Suppression of experimental allergic neuritis in rats by prior immunization with nerve in saline

  • James R. Lehrich
  • Barry G. Arnason
Original Investigations

Summary

Rats given nerve in saline intraperitoneally failed to develop allergic neuritis when challenged with nerve in adjuvant 2 weeks later. The serum of protected rats prevented sensitized lymph node cells, from rats immunized only with nerve in adjuvant, from demyelinating rat peripheral nerve cultures.

Key-Words

Allergic Neuritis Enhancement Demyelination Nerve Tissue Culture Delayed Hypersensitivity 

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Copyright information

© Springer-Verlag 1971

Authors and Affiliations

  • James R. Lehrich
    • 1
    • 2
  • Barry G. Arnason
    • 1
    • 2
  1. 1.Department of NeurologyMassachusetts General HospitalBostonUSA
  2. 2.Harvard Medical SchoolBoston

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