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Die zentrale Hörbahn beim Meerschweinchen

Eine Untersuchung mit [14C]2-Deoxyglucose

The auditory pathway in guinea pigs

A [14C]2-deoxyglucose study

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Summary

The auditory pathway of guinea pigs was labeled with [14C]-deoxyglucose after mon- or binaural stimulation with farfield white noise in a sound-proof chamber. In the autoradiographs, all auditory nuclei were labeled. The highest metabolic effects were seen in the dorsal cochlear nucleus, the lateral superior olivary nucleus, and in the inferior colliculus. No selective labeling was observed in the auditory cortex. Monaural stimulation depressed the metabolic activity contralaterally in the ventral cochlear nucleus and ipsilaterally in the medial nucleus of the trapezoid body, the dorsomedial periolivary nucleus, and in the inferior colliculus.

Zusammenfassung

Die zentrale Hörbahn wurde beim Meerschweinchen mit der [14C]2-Deoxyglucosemethode bei Ruhe sowie bei mon- und binauraler Stimulation markiert. Die Reizung erfolgte mit weißem Rauschen im freien Schallfeld. In den Autoradiogrammen waren alle akustischen Kerne markiert, den höchsten Stoffwechselumsatz zeigten nach Stimulation der dorsale Cochleariskern, der laterale Kern der oberen Olive und der Colliculus inferior. Der auditorische Cortex war von umgebenden Arealen nicht abgrenzbar. Monaurale Beschallung reduzierte die Markierung kontralateral im ventralen Cochleariskern sowie ipsilateral im medialen Trapezkern und dorsomedialen periolivären Kern sowie im Colliculus inferior.

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Herrn Prof. Dr. J. Staubesand zum 60. Geburtstag gewidmet

Mit Unterstützung der Deutschen Forschungsgemeinschaft, SFB 70

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Strutz, J., Beck, C. & Schmidt, C.L. Die zentrale Hörbahn beim Meerschweinchen. Arch Otorhinolaryngol 230, 27–36 (1981). https://doi.org/10.1007/BF00665377

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  • DOI: https://doi.org/10.1007/BF00665377

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