Abstract
The reaction of dimeric nitroso chlorides of olefins with potassium dithiocarbazate was used to synthesize 3-amino-4-hydroxylaminothiazolidine-2-thiones, which undergo rearrangement to 2-mercapto-1,3,4-thiadiazines on heating and react with butane-2,3-dione to give 2,3-dimethyl-4a,5-dihydro-7-thioxothiazolo[3,4-b]-1,2,4-triazine 4-oxides. The latter are reduced by sodium borohydride to the corresponding 3,4,4a,5-tetrahydro-7-thioxo derivatives.
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I. Beger and P. D. Thong, East German Patent No. 127811; Chem. Abstr., 88, 121250 (1978).
T. I. Orlova, S. P. épshtein, V. P. Tashchi, A. F. Rukasov, L. Ya. Bogel'fer, and Yu. G. Putsykin, Khim. Geterotsikl. Soedin., No. 4, 549 (1986).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 554–556, April, 1987.
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épshtein, S.P., Orlova, T.I., Rukasov, A.F. et al. Synthesis of 3-amino-4-hydroxylaminothiazolidine-2-thiones and 2,3-dimethyl-4a,5-dihydro-7-thioxothiazolo[3,4-b]-1,2,4-triazines. Chem Heterocycl Compd 23, 463–464 (1987). https://doi.org/10.1007/BF00546749
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DOI: https://doi.org/10.1007/BF00546749