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Reaction of substituted 2- and 4-methylpyrimidines with aromatic carboxylic acid chlorides

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The effect of substituants in methylpyrimidines on the reaction of the methyl groups with aromatic carboxylic acid chlorides in the presence of triethylamine was studied. It is shown that, depending on the character of the substituents, the reaction with the acid chlorides takes place at the methyl groups or at the ring nitrogen atoms.

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  1. V. M. Cherkasov, L. P. Prikazchikova, B. M. Khutova, I. F. Vladimirtsev, and I. V. Boldyrev, Khim. Geterotsikl. Soedin., No. 8, 1132 (1973).

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  2. L. P. Prikazchikova, B. M. Khutova, and V. M. Cherkasov, Khim. Geterotsikl. Soedin., No. 8, 1146 (1974).

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 687–690, May, 1982.

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Khutova, B.M., Klyuchko, S.V., Prikazchikova, L.P. et al. Reaction of substituted 2- and 4-methylpyrimidines with aromatic carboxylic acid chlorides. Chem Heterocycl Compd 18, 522–525 (1982). https://doi.org/10.1007/BF00526092

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  • DOI: https://doi.org/10.1007/BF00526092

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