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Reaction of 1-acyl-2-phenylpyrazolidines with imminium salts

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 1-acetyl-2-phenyl-4-methylpyrazolidine with imminium salts leads to the formation of 3-methyl-1,2,3,4-tetrahydropyrimido[1,2-a]-10-methylenedimethylimininium chloride, the alkaline hydrolysis of which gives 3-methyl-1,2,3,4-tetrahydropyrimido[1,2-a]-10-aldehyde. Similar reactions with 1-propionyl and 1-phenylacetyl derivatives leads to nonformylated indolization products. The relative reactivities of the imminium were studied.

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Authors and Affiliations

  1. M. V. Lomonosov Moscow State University, 117234, Moscow

    B. I. Gorin, G. A. Golubeva, L. A. Sviridova, A. V. Dovgilevich & Yu. G. Bundel

Authors
  1. B. I. Gorin
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  2. G. A. Golubeva
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  3. L. A. Sviridova
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  4. A. V. Dovgilevich
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  5. Yu. G. Bundel
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 397–401, March, 1983.

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Gorin, B.I., Golubeva, G.A., Sviridova, L.A. et al. Reaction of 1-acyl-2-phenylpyrazolidines with imminium salts. Chem Heterocycl Compd 19, 324–327 (1983). https://doi.org/10.1007/BF00513271

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  • DOI: https://doi.org/10.1007/BF00513271

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