Abstract
The first product under the conditions of O,S-arylation of monothiobarbituric acid is 5-aryl-hydrazonomonothiobarbituric acid. S-arylation then occurs to form the S-aryl ester of 5-arylhydrazonomonothiobarbituric acid. Further arylation leads to the O,S-diaryl esters of 5-arylhydrazonomonothiobarbituric acid. These esters are hydrolyzed under the influence of acids, alkalis, or hydrazine hydrate to thiophenols and phenols.
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We thank P.S. Pel'kis for his attention and interest in this research.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1271–1275, September, 1971.
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Nesynov, E.P., Besprozvannaya, M.M. Arylation of monothiobarbituric acid with arenediazonium salts. Chem Heterocycl Compd 7, 1194–1197 (1971). https://doi.org/10.1007/BF00510036
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DOI: https://doi.org/10.1007/BF00510036