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Synthesis of di- and tetrahydropyrroles

VIII. Synthesis and properties of 2,3,3-trimethyl-2-hydroxy-5-pyrrolidone

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A method for the synthesis of 2,3,3-trimethyl-2-hydroxy-5-pyrrolidone has been developed. 3,3-Dimethyl-2-methylene-5-pyrrolidone is initially formed during its thermolysis and then readily dimerizes. 2,3,3-Trimethyl-2-cyano-5-pyrrolidone was synthesized by the reaction of 2,3,3-trimethyl-2-hydroxy-5-pyrrolidone with potassium cyanide.

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Authors and Affiliations

  1. All-Union Scientific-Research Vitamin Institute, Moscow

    B. M. Sheiman, L. Ya. Denisova, S. F. Dymova, A. A. Shereshevskii, I. M. Kustanovich & V. M. Berezovskii

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  1. B. M. Sheiman
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  2. L. Ya. Denisova
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  3. S. F. Dymova
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  4. A. A. Shereshevskii
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  5. I. M. Kustanovich
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  6. V. M. Berezovskii
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Additional information

See [1] for communication VII.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1190–1193, September, 1971.

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Sheiman, B.M., Denisova, L.Y., Dymova, S.F. et al. Synthesis of di- and tetrahydropyrroles. Chem Heterocycl Compd 7, 1119–1122 (1971). https://doi.org/10.1007/BF00510016

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  • DOI: https://doi.org/10.1007/BF00510016

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