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Genetic variation of pepsinogen 1 in the rat

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Abstract

A pepsinogen (Pg 1) polymorphism was observed in gastric mucosal samples of Wistar rats by polyacrylamide slab gel electrophoresis. Three phenotypes were observed: S (a slow-moving band), F (a fast-moving band), and FS (both bands). Pg 1 variation was controlled by a pair of codominant alleles at a single autosomal locus. Interstrain variation of Pg 1 was studied in five strains of laboratory rats. Genetic variation of Pg 1 was detected only in the Wistar strain.

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Authors and Affiliations

  1. Faculty of Pharmaceutical Sciences, Josai University, Sakado, 350-02, Saitama, Japan

    Norio Muto & Satoru Tani

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  1. Norio Muto
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  2. Satoru Tani
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Muto, N., Tani, S. Genetic variation of pepsinogen 1 in the rat. Biochem Genet 20, 1189–1193 (1982). https://doi.org/10.1007/BF00498942

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  • DOI: https://doi.org/10.1007/BF00498942

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