Abstract
The nitration of 4-methyl-2,3-dihydro-1H-1,5-benzo-2-diazepinone gives the 7 nitro derivative. The 8-nitro isomer was obtained from 4-nitro-1,2-phenylenediamine. The catalytic hydrogenation of the nitrobenzodiazepinones gives the 7- and 8-amino derivatives. The nitrobenzodiazepinones exist in the enol form in alkaline media.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 833–837, June, 1974.
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Puodzhyunaite, B.A., Talaikite, Z.A. Synthesis of nitro-substituted 4-methyl-2,3-dihydro- and 2,3,4,5-tetrahydro-1H-1,5-benzo-2-diazepinones. Chem Heterocycl Compd 10, 724–727 (1974). https://doi.org/10.1007/BF00480936
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DOI: https://doi.org/10.1007/BF00480936