Abstract
The reaction of substituted 2-chlorocinchoninic acid amides with hydrazine hydrate or acylhydrazines gave 2-hydrazino- and 2-(Β-acylhydrazino)cinchoninic acid amides. The latter were also obtained by acylation of the 2-hydrazino derivatives. It is shown that 1,2,4-triazolo[4,3-a]quinoline-9-carboxylic acid amides are formed when 2-hydrazinocinchoninic acid amides are refluxed with formic or acetic acid.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
I. Werlei, A. Schauer, and G. Hartung, Klin. Wochenschr., 33, 562 (1955).
I. Büchi and H. Siegrist, Helv. Chim. Acta, 38, No. 3, 679 (1955).
O. A. Yanborisova, V. é. Kolla, S. A. Vikhareva, and M. E. Konshin, Khim.-farm. Zh., No. 2, 24 (1991).
Author information
Authors and Affiliations
Additional information
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 493–496, April, 1991.
Rights and permissions
About this article
Cite this article
Yanborisova, O.Y., Konshin, M.E. Synthesis of substituted 2-hydrazino- and 2-(Β-acylhydrazino)-cinchoninic acid amides and their cyclization to 1,2,4-triazolo[4,3-a]quinoline-9-carboxylic acid amides. Chem Heterocycl Compd 27, 390–394 (1991). https://doi.org/10.1007/BF00480836
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00480836