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Studies in the imidazole series

LVIII. Debenzylation of n-benzyl-substituted 1H-pyrrolo[1,2-a]imidazoles and 4H-pyrrolo[1,2-a]benzimidazoles

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Abstract

The debenzylation of N-benzyl-substituted 1H-pyrrolo[1,2-a]imidazoles and 4H-pyrrolo-[1,2-a]benzimidazoles under the influence of sodium in liquid ammonia was studied. From the IR and PMR spectra it was established that the compounds obtained have the structures of 7H-pyrrolo[1,2-a0]imidazole and 3H-pyrrolo[1,2-a]benzimidazole derivatives. The debenzylation of 2,3-diphenyl-4-benzylpyrrolo[1,2-a]benzimidazole proceeds with the simultaneous reduction of the pyrrole ring and the formation of 1H-2,3-dihydro-2,3-diphenylpyrrolo[1,2-a]benzimidazole.

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Authors and Affiliations

  1. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, Moscow

    P. M. Kochergin, Yu. N. Sheinker, A. A. Druzhinina, R. M. Palei & L. M. Alekseeva

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  1. P. M. Kochergin
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  2. Yu. N. Sheinker
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  3. A. A. Druzhinina
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  4. R. M. Palei
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  5. L. M. Alekseeva
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Additional information

See [1] for communication LVII.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 826–830, June, 1971.

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Kochergin, P.M., Sheinker, Y.N., Druzhinina, A.A. et al. Studies in the imidazole series. Chem Heterocycl Compd 7, 771–775 (1971). https://doi.org/10.1007/BF00476831

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  • DOI: https://doi.org/10.1007/BF00476831

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