Abstract
A number of higher aliphatic pyrryl ketones were synthesized. It is shown that a carbethoxy group in the 5 position of the pyrrole ring relatively weakly deactivates the 3 position of the ring to electrophilic attack during Friedel—Crafts acylation but hinders this reaction considerably when it is in the adjacent 4 position. The oxidation of the α-methyl group in a series of pyrryl ketones and the corresponding alcohols was studied.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 27–30, January, 1973.
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Mironov, A.F., Ol'shanskaya, N.B., Zhestkov, V.P. et al. Synthesis and some transformations of pyrroles with aliphatic acyl substituents. Chem Heterocycl Compd 9, 22–25 (1973). https://doi.org/10.1007/BF00476141
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DOI: https://doi.org/10.1007/BF00476141