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Synthesis of 4-Acyl-5-aryl-3-hydroxy-1-(3-picolyl)-3-pyrroline-2-ones

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Abstract

Reaction of methyl esters of acylpyruvic acids with a mixture of aromatic aldehyde and 3-picolylamine gave 5-aryl-4-acyl-3-hydroxy-1-(3-picolyl)-3-pyrroline-2-ones, the structure of which was confirmed on the basis of 1H NMR, 13C NMR, IR spectroscopy.

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Authors and Affiliations

  1. Perm State Pharmaceutical Academy, 614990, Perm, Russia

    V. L. Gein, N. V. Nosova, A. A. Cherepanov & K. D. Il’ina

  2. Perm State Medical University, 614990, Perm, Russia

    L. F. Gein

Authors
  1. V. L. Gein
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  2. N. V. Nosova
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  3. A. A. Cherepanov
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  4. L. F. Gein
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  5. K. D. Il’ina
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Correspondence to V. L. Gein.

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Gein, V.L., Nosova, N.V., Cherepanov, A.A. et al. Synthesis of 4-Acyl-5-aryl-3-hydroxy-1-(3-picolyl)-3-pyrroline-2-ones. Russ J Gen Chem 90, 579–582 (2020). https://doi.org/10.1134/S1070363220040039

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  • DOI: https://doi.org/10.1134/S1070363220040039

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