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One-pot synthesis of pyrroles from ketones, hydroxylamine, and 1,2-dibromoethane in the system KOH-DMSO

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Abstract

Dibutyl ketone, cyclohexanone, acetophenone, α-tetralone, and methyl 2-thienyl ketone were converted into the corresponding 2,3-substituted pyrroles by reaction with hydroxylamine hydrochloride and 1,2-dibromoethane in the system KOH-DMSO.

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Authors and Affiliations

  1. Favorskii Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, ul. Favorskogo 1, Irkutsk, 664033, Russia

    A. V. Ivanov, V. S. Shcherbakova, A. I. Mikhaleva & B. A. Trofimov

Authors
  1. A. V. Ivanov
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  2. V. S. Shcherbakova
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  3. A. I. Mikhaleva
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  4. B. A. Trofimov
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Corresponding author

Correspondence to B. A. Trofimov.

Additional information

Original Russian Text © A.V. Ivanov, V.S. Shcherbakova, A.I. Mikhaleva, B.A. Trofimov, 2014, published in Zhurnal Organicheskoi Khimii, 2014, Vol. 50, No. 12, pp. 1794–1797.

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Ivanov, A.V., Shcherbakova, V.S., Mikhaleva, A.I. et al. One-pot synthesis of pyrroles from ketones, hydroxylamine, and 1,2-dibromoethane in the system KOH-DMSO. Russ J Org Chem 50, 1775–1778 (2014). https://doi.org/10.1134/S1070428014120100

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  • DOI: https://doi.org/10.1134/S1070428014120100

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