Abstract
Reaction of 2-chloro-3-cyano-5,6,7,8-tetrahydroquinoline with arylamines gives 2-arylamino-3-cyano-5,6,7,8-tetrahydroquinolines, which on reaction with acetic anhydride or benzoyl chloride are converted into the N-acyl derivatives, and on further treatment with hydrogen chloride in anhydrous ethanol, into 2-substituted 1-aryl-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-4-ones.
Similar content being viewed by others
Literature Cited
N. I. Shramm and M. E. Konshin, Khim. Geterotsikl. Soedin., No. 1, 114 (1985).
N. I. Shramm and M. E. Konshin, Khim. Geterotsikl. Soedin., No. 5, 674 (1982).
Japanese Application No. 53-68788; Ref. Zh. Khim., No. 15, 0138P (1979).
Author information
Authors and Affiliations
Additional information
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 85–87, January, 1988.
Rights and permissions
About this article
Cite this article
Gavrilov, M.Y., Konshin, M.E. 2-Arylamino-3-Cyano-5,6,7,8-tetrahydroquinolines and 2-substituted 1-aryl-6,7,8,9-tetrahydropyrimido[4,5-b]-quinolin-4-ones derived therefrom. Chem Heterocycl Compd 24, 71–73 (1988). https://doi.org/10.1007/BF00475572
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00475572