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Synthesis of unsaturated ketones and derivatives of 2-pyrazoline containing an indole nucleus

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The crotonic condensation of 3-acetylindole, its N-methyl derivative, 3-formyl-1-methylindole, and 3-formyl-6-nitroindole with various aldehydes and methyl ketones in an alkaline medium has yielded a number of unsaturated ketones, some of which have been characterized as their 2, 4-dinitrophenylhydrazones. The reaction of some of these unsaturated ketones with phenylhydrazine has yielded derivatives of 1-phenyl-2-pyrazoline, which possess luminescent properties.

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References

  1. S. V. Tsukerman, V. M. Nikitchenko, A. I. Bugai, and V. F. Lavrushin, KhGS [Chemistry of Heterocyclic Compounds], 5, 268, 1969.

    Google Scholar 

  2. S. V. Tsukerman, V. P. Izvekov, and V. F. Lavrushin, KhGS [Chemistry of Heterocyclic Compounds], 1, 527, 1965.

    Google Scholar 

  3. P. Piozzi and C. Fuganti, Ann. chim., Rome, 56, 1248, 1966.

    Google Scholar 

  4. R. B. Order and H. C. Landwal, J. Org. Chem., 10, 128, 1945.

    Google Scholar 

  5. G. Jagal, Tetrah., 23, 2855, 1967.

    Google Scholar 

  6. J. Thesing, Chem. Ber., 87, 505, 1954.

    Google Scholar 

  7. S. V. Tsukerman, V. P. Izvekov, and V. F. Lavrushin, KhGS [Chemistry of Heterocyclic Compounds], 2, 387, 1966.

    Google Scholar 

  8. S. V. Tsukerman, V. P. Maslennikova, and V. F. Lavrushin, Opt. i spektr., 23, 396, 1967.

    Google Scholar 

  9. P. Piozzi and C. Fuganti, Ann. chim., Rome, 57, 486, 1967; RZhKh 4Zh347, 1968.

    Google Scholar 

  10. S. R. Sandler and S. Loshack, J. Phys. Chem., 66, 404, 1962.

    Google Scholar 

  11. S. V. Tsukerman, E. G. Buryakovskaya, Yu. S. Rozum, and V. F. Lavrushin, ZhPS, 8, 453, 1968.

    Google Scholar 

  12. L. Knorr, Ann., 238, 200, 1887.

    Google Scholar 

  13. F. Straus, Ber., 51, 1457, 1918.

    Google Scholar 

  14. Upjohn Co., British patent no. 869775, 1961; C. A., 3457, 1962.

  15. Yu. A. Baskakov and N. N. Mel'nikova, ZhOKh, collection 1, 712, 1953.

    Google Scholar 

  16. V. M. Rodionov and T. K. Veselovskaya, ZhOKh, 20, 2202, 1950.

    Google Scholar 

  17. W. E. Noland and R. D. Rieke, J. Org. Chem., 27, 2250, 1962.

    Google Scholar 

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Authors and Affiliations

  1. Gor'kii Khar'kov State University, USSR

    S. V. Tsukerman, A. I. Bugai, V. M. Nikitchenko & V. F. Lavrushin

Authors
  1. S. V. Tsukerman
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  2. A. I. Bugai
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  3. V. M. Nikitchenko
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  4. V. F. Lavrushin
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Tsukerman, S.V., Bugai, A.I., Nikitchenko, V.M. et al. Synthesis of unsaturated ketones and derivatives of 2-pyrazoline containing an indole nucleus. Chem Heterocycl Compd 6, 370–373 (1970). https://doi.org/10.1007/BF00471244

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  • DOI: https://doi.org/10.1007/BF00471244

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