Abstract
A study has been made of the condensation of serotonin with aldehydes to give the corresponding β-carboline derivatives. In most cases the reaction was run under biological conditions (pH 5. 4, 36‡). The following aldehydes were reacted: acetaldehyde, butyraldehyde, isobutyraldehyde, benzaldehyde, n-octaldehyde, and formaldehyde. The corresponding β-carboline derivatives are obtained from the first 5 of these. The reaction with formaldehyde leads to complete resinification.
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Petrova, M.F., Kaverina, N.S. & Men'shikov, G.P. Synthesis of carboline bases. Chem Heterocycl Compd 3, 684–685 (1967). https://doi.org/10.1007/BF00468345
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DOI: https://doi.org/10.1007/BF00468345