, Volume 59, Issue 2, pp 157–160 | Cite as

Facilitating effects of chlordiazepoxide on locomotor activity and avoidance behaviour of reserpinized mice

  • Mario Sansone
Original Investigations


Chlordiazepoxide increased the spontaneous locomotor activity of both normal and reserpinized mice and facilitated the avoidance behaviour of mice pretreated with reserpine. These effects of chlorodiazepoxide on reserpinized animals were unexpected, since they are usually considered characteristic of antidepressant drugs.

Key words

Chlordiazepoxide Reserpine Locomotor activity Avoidance behaviour Mice 


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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • Mario Sansone
    • 1
  1. 1.Laboratorio di Psicobiologia e PsicofarmacologiaC.N.R.RomaItaly

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