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Effects of N-(ethyl-2 pyrrolidinyl-methyl)-2-methoxy-5-sulfamoil-benzamide (sulpyrid) on the central nervous system in rats and mice

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Abstract

Sulpyrid is a new psychoactive drug and several clinical studies indicate a series of polymorphic therapeutic indications.

Experimentally, sulpyrid blocks muricide reactions by isolation in rats but it is not active on aggressiveness in mice. Sulpyrid also modifies the exploratory activity in mice in which it decreases the brain 5-hydroxytryptamine turnover, as well as in rats.

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Valzelli, L., Bernasconi, S. Effects of N-(ethyl-2 pyrrolidinyl-methyl)-2-methoxy-5-sulfamoil-benzamide (sulpyrid) on the central nervous system in rats and mice. Psychopharmacologia 26, 255–261 (1972). https://doi.org/10.1007/BF00422701

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  • DOI: https://doi.org/10.1007/BF00422701

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