Skip to main content
Log in

Enzymic and ultrastructural changes in rat liver due to whole body vibration

  • Published:
International Archives of Occupational and Environmental Health Aims and scope Submit manuscript

Summary

By applying biochemical, histochemical and electron microscopical methods the authors studied the effect of the whole body vertical sinusoidal vibration (100 Hz 0,1 mm) on rat liver. The activity of SDH and ATP-ase was significantly decreased, whereas the G1-6-PDH and LDH was markedly increased in liver homogenates and kryostate slices. Certain abnormalities concerning the number, size and internal organization of the mitochondria were observed. The data revealed by the biochemical, histochemical and ultrastructural study show the possibility of involvement of liver tissue in vibration caused damages.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Abramovich-Poljakov, D.K., Gunko, M.V., Perly, O.N.: Some indices of the energetic turnover with vibration diseases. Gig. truda i profzabol. 8, 34–36 (1974) (in Russian)

    Google Scholar 

  2. Andreeva-Galanina E. Ts., Dolgova, M.A., Jakubovich, T.G.: The effect of the whole-body vertical vibration on the vascular stream of the liver. Gig. truda i profzabol. 12, 22–24 (1971) (in Russian)

    Google Scholar 

  3. Chramov, J.A.: Peculiarities of glucose consumption, lactic and pyruvic acid in persons exposed to vibration. Gigiena i sanitaria 1, 110–112 (1975) (in Russian)

    Google Scholar 

  4. Ivanovich, E.: Experimental investigation on the changes in rat kidney, due to whole body vibration. Dissertation, Sofia (1970)

  5. Ivanovich, E., Zlateva, M.: Dynamics of recovery processes in rat liver under the effect of low-frequency vibrations. Proceed. Regional Symposium on Noise and Vibration Abatement of the COPISEE Member-countries. Varna 30.10-1.11, 1971, p. 31–35

  6. Ivanovich, E., Krastev, L.: Ultrastructural changes in rat liver due to wholebody vibration and physical loading. Proceed. Regional Symposium on Noise and Vibration Abatement of the COPISEE Member-countries. Varna, 14–18.10.1975

  7. Karpova, N., Kordykov, N., Ivanova, V.: The effect of local vibration on the blood vessels and peripheral nerves. Gig. truda i profzabol. 18/8, 4–7 (1974)(in Russian)

    Google Scholar 

  8. Kirk, J., Laursen, T.: Dehydrogenase activities of human aortic tissue determined with triphenyl tetrazolium technique. J. of Gerontol. 10, 1, 18–25 (1955)

    Google Scholar 

  9. Kiseleva, B.P., Bulachenko, L.S.: Disturbance in some indices of protein metabolism after a prolonged vibration effect. Gig. truda i profzabol. 8, 38–41 (1974) (in Russian)

    Google Scholar 

  10. Lind, H.: About the activity of urease and ATP-ase in subcellular fractions of ventricular mucosis. Biochimija, Moscow, 29, 2, 191 (1964) (in Russian)

    Google Scholar 

  11. Miclesco-Groholsky, S., Anitesco, C.: Variations de l'anylasarie de l'amylasemie sous l'effet du “stress” sonore et vibratoire dans l'industrie. Arch. Mal. Prof. 31, 6 277–282 (1970)

    Google Scholar 

  12. Molchanov, B.P., Solun, B.S.: Changes in the protein metabolism in vibration disease. Gig. truda i profzabol. 10, 43–45 (1971) (in Russian)

    Google Scholar 

  13. Mori, M.: Histochemical evaluation of NAD-P-dependent glucose-6-phosphate and isocitrate dehydrogenases in steroid producing organs and tumors. Arch. Histol. Jap. 28, 45–57 (1967)

    Google Scholar 

  14. Nachlas, M.M., Tsou, L.C., Souza, E.D., Cheng, C.S., Seligman, A.M.: Cytochemical demonstration of succinic dehydrogenase by use of a new p-nitrophenyl substituted ditetrazole, J. Histochem., Cytochem. 5, 420–436 (1957)

    Google Scholar 

  15. Padykula, A.A., Herman, E.: Factors affecting the activity of ATP-ase and other phosphatases as measured by histochemical techniques. J. Histochem. Cytochem. 3, 161–169 (1955)

    Google Scholar 

  16. Pogodaev, K.T., Turova, N.P.: in “Brain biochemistry under fatigue and exhaustion”. Moscow: Medicina 1972 (in Russian)

    Google Scholar 

  17. Sass, D.J.: Mechanisms of injury due to intense ± Gz vibration in waterimmersed cats. J. App. Physiol. 26,6, 819–826 (1969)

    Google Scholar 

  18. Slateva, M., Ivanovich, E., Antov, G.: Histological and enzymic investigation in rat liver due to vibration. Higiena i zdraveopazvane XIV, 2, 161–166 (1971) (in Bulgarian)

    Google Scholar 

  19. Sobol, J.M., Jenin, J.P.: Electron microscopic changes in the Cochlea after exposure to whole body vibration and noise. Zh. Ushn. Nos. Gorl. Bolezn, 32/6, 43–48 (1972)

    Google Scholar 

  20. Tsvetkov, D.L., Hadzieva, I., Calbourova, F., Georgieva, I.: Modifications de certains indices de l'oxydation biologique et de la phosphorylation sous l'influence de vibrations experimentales de haute frequence. Int. Arch. Occup. Environm. Hlth. 35, 265–277 (1975)

    Google Scholar 

  21. Tsvetkov, D.L., Popov, T.: The effect of high-frequency vibration on the activity of some enzymes participating in biological oxidation in experiment. J. Hygiene, Epidemiology, Microbiol. Immunil. 17, 169–175 (1973)

    Google Scholar 

  22. Tambovtseva, A.M.: The effect of vibration and noise on protein metabolism in excavator operators judging by certain biochemical indices. Gig. i sanitaria 1, 58–61 (1968) (in Russian)

    Google Scholar 

  23. Verzilova, O.V., Rodnikov, A., Razbash, F.L.: Impact of prolonged continuous and interrupted exposure to general vertical vibration on human organism. Biul. Inst. Med. Morsk. Gdansk. 25/2-3-4, 375–378 (1974)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ivanovich, E., Antov, G. & Kazakova, B. Enzymic and ultrastructural changes in rat liver due to whole body vibration. Int. Arch Occup Environ Heath 39, 249–254 (1977). https://doi.org/10.1007/BF00409370

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00409370

Key words

Navigation