Summary
The neurohypophysis of foetal macaque monkeys has been studied by optical and electron microscopy. Abundant elementary neurosecretory granules are present in the infundibular process by the middle third of gestation. Most of these are of variable electron density, and surrounded by a membrane larger than the granule, so that they appear haloed. A few fibres contain membrane-bounded electron-dense granules which show no halo. Inclusions of “synaptic vesicle” size are rare. The infundibular stem contains a few fibres with typical inclusions smaller than 1000 Å in diameter; the latter resemble inclusions in fibres of the median eminence.
Similar content being viewed by others
References
Barbour, H. G., and W. F. Hamilton: The falling drop method for determining specific gravity. J. Amer. med. Ass. 88, 91–94 (1927).
Bargmann, W.: Über die neurosekretorische Verknüpfung von Hypothalamus und Neurohypophyse. Z. Zellforsch. 34, 610–634 (1949).
—: Das Zwischenhirn-hypophysensystem. Berlin-Göttingen-Heidelberg: Springer 1954.
Heller, H., and K. Lederis: Maturation of the hypothalamo-neurohypophysial system. J. Physiol. (Lond.) 147, 299–314 (1959).
Holmes, R. L.: Comparative observations on inclusions in nerve fibres of the mammalian neurohypophysis. Z. Zellforsch. 64, 474–492 (1964).
Lederis, K.: An electron microscopical study of the human neurohypophysis. Z. Zellforsch. 65, 847–868 (1965).
Palay, S. L.: The fine structure of the neurohypophysis. In: Progress in Neurobiology II. Ultrastructure and cellular chemistry of neural tissue, p. 31–44 (Ed. H. Waelsch). New York 1957.
Schultz, A. H.: Fetal growth and development of the Rhesus monkey. Contr. Embryol. Carneg. Instn 155, 71–97 (1937).
Wurster, D. H., and K. Benirschke: Development of the hypothalamo-hypophysial neurosecretory system in the fetal armadillo (Dasypus novemcinctus) with notes on rabbit, cat and dog. Gen. comp. Endocr. 4, 433–441 (1964).
Author information
Authors and Affiliations
Additional information
Dedicated to Professor W. Bargmann on his 60th birthday.
Rights and permissions
About this article
Cite this article
Holmes, R.L. The neurohypophysis of the foetal monkey. Z.Zellforsch 69, 288–295 (1966). https://doi.org/10.1007/BF00406281
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00406281