Summary
Exposure of DMF (dimethylformamide) and urinary MF (methyl-formamide-metabolite of DMF) were measured in nine male workers handling surface-treating agents containing DMF for 5 consecutive days. The amount of urinary MF correlated well with the exposure to DMF. The measurement of urinary MF is therefore useful as an index of exposure to DMF.
The rate constant for MF excretion was estimated as 0.16/h, while that calculated from Krivanek's data averaged 0.21/h. The MF excretion delay was correlated with the daily alcohol consumption.
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Yonemoto, J., Suzuki, S. Relation of exposure to dimethylformamide vapor and the metabolite, methylformamide, in urine of workers. Int Arch Occup Environ Health 46, 159–165 (1980). https://doi.org/10.1007/BF00378194
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DOI: https://doi.org/10.1007/BF00378194