Abstract
Extraction of lactic acid from fermentation broths have been studied. The extractant selected for this research was paraffin oil which, in addition to having satisfactory physical properties, is non-toxic and does not affect the fermentability of the broth. Several amine compounds and a polymeric resin (Bonopore) have been tested to increase the extraction efficiency of the paraffin oil. Addition of these compounds gave higher K D values. However, all of the amine compounds tested are highly toxic to the free cells of L. delbrueckii (NRRL B-445). Bonopore, the polymer giving good absorption pattern and no deleterious effects was tested with paraffin oil in repeated batch culture of L. delbrueckii.
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Seevaratnam, S., Holst, O., Hjörleifsdottir, S. et al. Extractive bioconversion for lactic acid production using solid sorbent and organic solvent. Bioprocess Eng. 6, 35–41 (1990). https://doi.org/10.1007/BF00369276
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DOI: https://doi.org/10.1007/BF00369276