Summary
The “sucrose-gap“ method of Stämpfli (1954) has been modified by the arrangement of two sucrose-gaps on both sides of a segment of a bundle of myelinated nerve fibres. This new method is convenient not only for measuring changes of membrane potential but also for examination of membrane resistance and action potential. On the average, 80% of the true changes of membrane potential can be recorded. The action potentials are strictly monophasic, their amplitude being about 80 mV, their duration 1–2 msec. Changes in membrane resistance are determined by recording current-voltage curves under various experimental conditions.
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Schmidt, H. Messung von Änderungen des Membranwiderstandes markhaltiger Nervenfasern mit der „Saccharose-Trennwand“-Methode. Pflügers Archiv 274, 632–641 (1962). https://doi.org/10.1007/BF00363151
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DOI: https://doi.org/10.1007/BF00363151